Ole Miss vs. Iowa State Picks and Prediction – 3/23/2025

No. 6 Ole Miss Rebels (22-11, 11-7 SEC) vs. No. 3 Iowa State Cyclones (24-9, 12-6 Big 12)
Time: 7:45 PM
Location: Fiserv Forum, Milwaukee, WI

Previous Games:
Ole Miss: 71-64 win over North Carolina in the first round of the NCAA Tournament
Iowa State: 82-55 win over Lipscomb in the first round of the NCAA Tournament

Head-to-Head:
Iowa State won 76-69 in their last matchup

Key Stats & Trends:
Iowa State has allowed just 68.1 points per game this season
Ole Miss struggled from the free-throw line, hitting just 65.2% of their foul shots

Ole Miss Breakdown:
Ole Miss enters this game after holding on to defeat North Carolina despite nearly squandering a 22-point lead. Sean Pedulla led the Rebels in scoring with 20 points, while Dre Davis contributed with 15 points and eight rebounds. Despite their win, Ole Miss will need to improve their free-throw shooting (65.2%) if they hope to compete with Iowa State’s efficient offense and defense.

Iowa State Breakdown:
Iowa State looked impressive in their dominant win over Lipscomb, with Milan Momcilovic leading the Cyclones with 20 points. Curtis Jones added 17 points, while the team shot an outstanding 58.3% from the field. Iowa State’s strong defense, which allowed an average of just 68.1 points per game this season, will be key in containing Ole Miss’ offense.

Exact Score Prediction:
Iowa State 73 - Ole Miss 65

Our Best Bet:
Iowa State -5.5 @ -110